Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115364 | 0.85 | LMNA (0.46) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL26315999 | 0.81 | TSHR (0.44) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL11058491 | 0.77 | TSHR (0.40) | LMNATSHRKDM4EMEN1KMT2A | |
| SCHEMBL645857 | 0.75 | TDP1 (0.41) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL7651937 | 0.74 | TDP1 (0.43) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL5085700 | 0.74 | LMNA (0.42) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL5607572 | 0.74 | LMNA (0.47) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL24033557 | 0.73 | TSHR (0.41) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL11056105 | 0.73 | GAA (0.44) | LMNATSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL11055977 | 0.73 | TSHR (0.36) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487781-A | HEAT RESISTANCE; PHOTOSTABILITY | SANKYO COMPANY LIMITED (JP) | 1984-12-11 | — | — | US | disclosed |