Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12588874 | 0.89 | TSHR (0.43) | LMNAMAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL11115364 | 0.87 | LMNA (0.46) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL128878 | 0.83 | LMNA (0.41) | LMNAMAPTTSHRALDH1A1MGAM | |
| SCHEMBL10907112 | 0.82 | ALDH1A1 (0.33) | LMNATSHRTDP1ALDH1A1MGAM | |
| SCHEMBL16861340 | 0.82 | USP2 (0.33) | LMNATSHRTDP1ALDH1A1MGAM | |
| SCHEMBL5606265 | 0.82 | LMNA (0.48) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL7651937 | 0.81 | TDP1 (0.43) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL5085700 | 0.81 | LMNA (0.42) | LMNAMAPTTSHRTDP1CYP2D6 | |
| SCHEMBL9937292 | 0.80 | FAAH (0.31) | LMNATSHRTDP1ALDH1A1MGAM | |
| SCHEMBL11912087 | 0.79 | MAPT (0.43) | LMNAMAPTTSHRTDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075062-C | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | claimed |
| CN-1112104-A | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 1995-11-22 | — | — | CN | claimed |
| CN-110546568-A | Composition for forming coating film on substrate having level difference, comprising plasma-curable compound using unsaturated bond between carbon atoms | NISSAN CHEMICAL CORP | 2019-12-06 | — | — | CN | disclosed |
| CN-110475473-A | Containing monoterpene/Phenylpropanoid Glycosides compound and preparation method thereof and as the purposes of insecticide | KITTRICH CORP | 2019-11-19 | — | — | CN | disclosed |
| CN-105153192-B | Substituted tetrahydro thienopyridine derivative and its application | 南京曼杰生物科技有限公司 | 2019-03-29 | — | — | CN | disclosed |
| US-10017499-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170114046-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARM INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-9472813-B2 | Battery electrolyte solution containing certain ester-based solvents, and batteries containing such an electrolyte solution | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-10-18 | — | — | US | disclosed |
| CN-105940060-A | Aqueous coating composition for dip coating of electrically conductive substrates containing bismuth and a phosphorus-containing amine-blocked compound | 巴斯夫涂料有限公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-105814147-A | Aqueous coating composition comprising bismuth in dissolved and undissolved form for dip coating electrically conductive substrates | 巴斯夫涂料有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105765007-A | Aqueous coating composition comprising magnesium oxide for dip coating of electrically conductive substrates | 巴斯夫涂料有限公司 | 2016-07-13 | — | — | CN | disclosed |
| US-8044230-B2 | Hydrolytic stability needed to maintain the prodrug in solution in the subject's system until appropriate conditions exist when the prodrug can hydrolyze, releasing the active compound | INTERVET INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-08-07 | — | — | US | disclosed |
| US-20080153906-A1 | Water-Soluble Phenicol Prodrugs in a Lipophilic Vehicle System | INTERVET INC. | 2008-06-26 | — | — | US | disclosed |
| US-20080146640-A1 | Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof | SCHERING-PLOUGH LTD. (CH) | 2008-06-19 | — | — | US | disclosed |
| US-20070142472-A1 | Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
| EP-1687250-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | Takasago International Corporation (JP) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051882-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-09 | — | — | WO | disclosed |
| CN-1075062-C | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | disclosed |
| CN-1112104-A | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 1995-11-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114046-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | LMNA 3064/4885MAPT 4471/4885TSHR 4648/4885 |
| US-20080153906-A1 | Water-Soluble Phenicol Prodrugs in a Lipophilic Vehicle System | BPHL, CYP4B1, CYP4A22 | LMNA 614/4885MAPT 1057/4885TSHR 2907/4885 |
| US-10017499-B2 | Benzimidazole derivatives | EIF2AK2, ZC3HAV1, ZC3HAV1L | LMNA 2786/4885MAPT 4391/4885TSHR 4619/4885 |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | PFAS, ADH5, SI | LMNA 2524/4885MAPT 2357/4885TSHR 3559/4885 |
| US-20080146640-A1 | Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof | TREH, ADH5, CES2 | LMNA 3313/4885MAPT 2293/4885TSHR 1911/4885 |
| US-20070142472-A1 | Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids | ALDH1A2, ALDH1A3, GRHPR | LMNA 1420/4885MAPT 4570/4885TSHR 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.