Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HK2 | P52789 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30203505 | 0.82 | IAPP (0.68) | IAPPALDH1A1HSD17B10 | |
| SCHEMBL490950 | 0.82 | POLB (0.50) | IAPP | |
| SCHEMBL6789908 | 0.81 | CA2 (0.45) | ESR1ADORA3NPY1RPTGS2OPRD1 | |
| SCHEMBL26046412 | 0.80 | IAPP (0.70) | IAPPPRKCIALDH1A1 | |
| SCHEMBL22290157 | 0.79 | IAPP (0.36) | IAPPESR1ADORA3NPY1RPTGS2 | |
| SCHEMBL23816613 | 0.77 | PIK3CA (0.49) | IAPP | |
| SCHEMBL11058348 | 0.74 | TYR (0.63) | — | |
| SCHEMBL29131809 | 0.74 | IAPP (0.58) | IAPPPRKCI | |
| SCHEMBL28475321 | 0.74 | SELL (0.45) | — | |
| SCHEMBL5463172 | 0.74 | TAAR1 (0.52) | MTORKDM4EALDH1A1THPOHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448730-A | ANTITUMOR AGENTS | RIET BARTHOLOMEUS VAN T | 1984-05-15 | — | — | US | disclosed |