Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HK2 | P52789 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029713 | 0.83 | GAA (0.53) | CA2ALDH1A1HSD17B10GAANPSR1 | |
| SCHEMBL28994842 | 0.82 | SELL (0.41) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL22982305 | 0.81 | SELL (0.44) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL31618870 | 0.81 | SELL (0.44) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL11051603 | 0.81 | IAPP (0.46) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL8685874 | 0.79 | AKR1B1 (0.58) | CA2KDM4ETHPOHSD17B10GAA | |
| SCHEMBL30940438 | 0.79 | AKR1B1 (0.58) | CA2KDM4ETHPOHSD17B10GAA | |
| SCHEMBL660344 | 0.77 | IAPP (0.46) | ESR2ESR1ADORA3NPY1RPTGS2 | |
| SCHEMBL9313934 | 0.77 | ESR2 (0.37) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL11058291 | 0.77 | CA2 (0.40) | CA2KDM4EALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6803367-B2 | ANTICANCER AGENTS; SYNERGISTIC MIXTURES | TAKARA SHUZO CO., LTD. (JP) | 2004-10-12 | — | — | US | disclosed |
| CN-1125023-C | Apoptosis inducer | TAKARA SHUZO CO (JP) | 2003-10-22 | — | — | CN | disclosed |
| US-20030065014-A1 | Substance for inducing apoptosis | TAKARA BIO INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6525082-B1 | 2-hydroxy-4-(1-imidazolyl)-2-cyclopenten-1-one; inhibiting growth of cancer cells | TAKARA SHUZO CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| CN-1281426-A | Substance inducing apoptosis | TAKARA SHUZO CO (JP) | 2001-01-24 | — | — | CN | disclosed |
| EP-1048641-A1 | APOPTOSIS INDUCER | Takara Shuzo Co, Ltd. (JP) | 2000-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065014-A1 | Substance for inducing apoptosis | BAX, BCL2, BAD | CA2 3685/4885ESR2 1567/4885KDM4E 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.