SCHEMBL5463172

SCHEMBL5463172

NCCc1ccc(O)c(O)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.52
RECQL P46063 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
MEN1 O00255 2/20 0.48
RAD52 P43351 2/20 0.48
KMT2A Q03164 2/20 0.48
APEX1 P27695 2/20 0.48
GAPDH P04406 1/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
KDM4E B2RXH2 2/20 0.46
MAPT P10636 2/20 0.46
ALOX15 P16050 2/20 0.46
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 2/20 0.46
AGO2 Q9UKV8 1/20 0.46
HMGB1 P09429 1/20 0.46
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.45
ADRB2 P07550 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265021 0.80 TAAR1 (0.47) TAAR1RECQLTDP1MEN1RAD52
SCHEMBL19064575 0.80 TAAR1 (0.48) TAAR1RECQLTDP1MEN1RAD52
SCHEMBL29597839 0.80 TAAR1 (0.48) TAAR1RECQLTDP1MEN1RAD52
SCHEMBL272405 0.80 TYR (0.48)
SCHEMBL633722 0.80 ESR2 (0.40) TDP1MEN1KMT2AKDM4EMAPT
SCHEMBL29531687 0.79 TAAR1 (0.68) TAAR1RECQLTDP1MEN1RAD52
SCHEMBL68660 0.79 TAAR1 (0.68) TAAR1RECQLTDP1MEN1RAD52
Hydrochloric Acid SCHEMBL19385313 0.79 TAAR1 (0.47) TAAR1RECQLTDP1MEN1RAD52
Hydrochloric Acid SCHEMBL3572840 0.78 KDM4E (0.41) TDP1MEN1KMT2AKDM4EMAPT
SCHEMBL30045892 0.78 KDM4E (0.43) TDP1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10259894-B1 Oxygen permeable polymers, ionomers and methods of making the same NISSAN NORTH AMERICA, INC. (US) 2019-04-16 US claimed
US-20190092882-A1 Oxygen Permeable Monomers, Polymers and Ionomers and Methods of Making the Same NISSAN MOTOR CO., LTD. (JP) 2019-03-28 US claimed
CN-118745137-A Diamine monomer and polyimide containing polyphenol, and preparation methods and applications thereof 天津科技大学 2024-10-08 CN disclosed
CN-118745139-A Diamine monomer and polyimide containing flexible side chains, and preparation methods and applications thereof 天津科技大学 2024-10-08 CN disclosed
US-10259894-B1 Oxygen permeable polymers, ionomers and methods of making the same NISSAN NORTH AMERICA, INC. (US) 2019-04-16 US disclosed
US-20190092882-A1 Oxygen Permeable Monomers, Polymers and Ionomers and Methods of Making the Same NISSAN MOTOR CO., LTD. (JP) 2019-03-28 US disclosed
US-20160372339-A1 SEMICONDUCITIVE CATECHOL GROUP ENCAPSULANT ADHESION PROMOTER FOR A PACKAGED ELECTRONIC DEVICE NXP USA, INC. 2016-12-22 US disclosed
US-9466544-B2 Semiconducitive catechol group encapsulant adhesion promoter for a packaged electronic device FREESCALE SEMICONDUCTOR, INC. (US) 2016-10-11 US disclosed
US-20140210063-A1 SEMICONDUCITIVE CATECHOL GROUP ENCAPSULANT ADHESION PROMOTER FOR A PACKAGED ELECTRONIC DEVICE NXP, B.V. F/K/A FREESCALE SEMICONDUCTOR, INC. (NL) 2014-07-31 US disclosed
US-20070190187-A1 FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE KNELLER BRUCE W 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070190187-A1 FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE MAOB, PNMT, MAOA TAAR1 333/4885RECQL 2937/4885TDP1 1014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.