Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.61 |
| ▸ | EBP | Q15125 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652227 | 0.86 | SIGMAR1 (0.71) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL42095 | 0.82 | OPRM1 (0.65) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL11659331 | 0.80 | OPRM1 (0.65) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL11654239 | 0.78 | OPRM1 (0.61) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| Carbamic Acid SCHEMBL6120538 | 0.77 | OPRM1 (0.62) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL13828268 | 0.77 | SIGMAR1 (0.77) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| (+)-Pentazocine SCHEMBL16220021 | 0.77 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| (+)-Pentazocine SCHEMBL18672553 | 0.77 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| (+)-Pentazocine SCHEMBL4376337 | 0.77 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| Rel-Pentazocine SCHEMBL135685 | 0.77 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464378-A | Method of administering narcotic antagonists and analgesics and novel dosage forms containing same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1984-08-07 | — | — | US | disclosed |
| EP-0077393-A1 | NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME | The University of Kentucky Research Foundation (US) | 1983-04-27 | — | — | EP | disclosed |
| WO-1982003768-A1 | NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME | UNIV KENTUCKY (US) | 1982-11-11 | — | — | WO | disclosed |