Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.62 |
| ▸ | EBP | Q15125 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11654239 | 0.90 | OPRM1 (0.61) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL11652227 | 0.87 | SIGMAR1 (0.71) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL42095 | 0.83 | OPRM1 (0.65) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| Carbamic Acid SCHEMBL6120538 | 0.81 | OPRM1 (0.62) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL11051972 | 0.80 | OPRM1 (0.61) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL16557090 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL20820889 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL16558076 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL19199921 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 | |
| SCHEMBL16451305 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105659-A | ANTAGONISTS, ANALGESICS | STERLING DRUG INC. (US) | 1978-08-08 | — | — | US | disclosed |