SCHEMBL42095

SCHEMBL42095

CC(C)=CCN1CCC2(C)c3cc(OC(=O)C(C)O)ccc3CC1C2C

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 6/20 0.65
OPRD1 P41143 4/20 0.65
OPRK1 P41145 4/20 0.65
SIGMAR1 Q99720 11/20 0.65
TMEM97 Q5BJF2 4/20 0.65
EBP Q15125 1/20 0.65
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11652227 0.90 SIGMAR1 (0.71) OPRM1OPRD1OPRK1SIGMAR1TMEM97
SCHEMBL7211284 0.86 SIGMAR1 (0.52) OPRM1OPRD1OPRK1SIGMAR1
Pentazocine SCHEMBL16107180 0.83 SIGMAR1 (0.83) OPRM1OPRD1OPRK1SIGMAR1TMEM97
(+)-Pentazocine SCHEMBL42094 0.83 SIGMAR1 (0.83) OPRM1OPRD1OPRK1SIGMAR1TMEM97
(+)-Pentazocine SCHEMBL3665045 0.83 SIGMAR1 (0.83) OPRM1OPRD1OPRK1SIGMAR1TMEM97
SCHEMBL11659331 0.83 OPRM1 (0.65) OPRM1OPRD1OPRK1SIGMAR1TMEM97
SCHEMBL11051972 0.82 OPRM1 (0.61) OPRM1OPRD1OPRK1SIGMAR1TMEM97
SCHEMBL10031232 0.81 SIGMAR1 (0.75) OPRM1OPRD1OPRK1SIGMAR1TMEM97
SCHEMBL11654239 0.81 OPRM1 (0.61) OPRM1OPRD1OPRK1SIGMAR1TMEM97
Carbamic Acid SCHEMBL6120538 0.80 OPRM1 (0.62) OPRM1OPRD1OPRK1SIGMAR1TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 963 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115737571-A Pentazocine preparation and preparation method and application thereof 广州市力鑫药业有限公司 2023-03-07 CN claimed
US-10925864-B2 Stable liquid injectable solution of midazolam and pentazocine NEON LABORATORIES LIMITED (IN) 2021-02-23 US claimed
WO-2008116165-A9 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION NEXT SAFETY INC (US) 2009-06-11 WO claimed
WO-2008116165-A2 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION NEXT SAFETY, INC. (US) 2008-09-25 WO claimed
US-20080066741-A1 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION HUNTER, CHARLES ERIC 2008-03-20 US claimed
EP-1416920-B1 MULTIPLEX DRUG DELIVERY SYSTEM SUITABLE FOR ORAL ADMINISTRATION IMPAX PHARMACEUTICALS INC (US) 2007-01-10 EP claimed
EP-1416920-A4 MULTIPLEX DRUG DELIVERY SYSTEM SUITABLE FOR ORAL ADMINISTRATION IMPAX PHARMACEUTICALS INC (US) 2004-05-12 EP claimed
EP-1416920-A2 MULTIPLEX DRUG DELIVERY SYSTEM SUITABLE FOR ORAL ADMINISTRATION Impax Pharmaceuticals Inc. (US) 2004-05-12 EP claimed
US-6730321-B2 FOR TABLETS; COMPRESSION BLEND; SUSTAINED RELEASE IMPAX PHARMACEUTICALS, INC. 2004-05-04 US claimed
US-20030203028-A1 Multiplex drug delivery system suitable for oral administration IMPAX PHARMACEUTICALS, INC. 2003-10-30 US claimed
US-20020164371-A1 Press coated, pulsatile drug delivery system suitable for oral administration IMPAX PHARMACEUTICALS INC. 2002-11-07 US claimed
US-6372254-B1 Press coated, pulsatile drug delivery system suitable for oral administration IMPAX PHARMACEUTICALS INC. 2002-04-16 US claimed
WO-2000018447-A2 MULTIPLEX DRUG DELIVERY SYSTEM SUITABLE FOR ORAL ADMINISTRATION IMPAX PHARMACEUTICALS, INC. (US) 2000-04-06 WO claimed
WO-1999051209-A1 PRESS COATED, PULSATILE DRUG DELIVERY SYSTEM SUITABLE FOR ORAL ADMINISTRATION IMPAX PHARMACEUTICALS, INC. (US) 1999-10-14 WO claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed
US-20260144746-A1 Protein Based Soft Chew Tablets FERTIN PHARMA A/S (DK) 2026-05-28 US disclosed
US-20260144745-A1 Sugar Free Soft Chew Tablets FERTIN PHARMA A/S (DK) 2026-05-28 US disclosed
EP-0077393-A1 NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME The University of Kentucky Research Foundation (US) 1983-04-27 EP disclosed
WO-1982003768-A1 NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME UNIV KENTUCKY (US) 1982-11-11 WO disclosed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144745-A1 Sugar Free Soft Chew Tablets SI, TREH, SLC2A3 OPRM1 1446/4885OPRD1 1740/4885OPRK1 897/4885
US-20260144746-A1 Protein Based Soft Chew Tablets CARHSP1, HIRA, HEATR6 OPRM1 1937/4885OPRD1 2393/4885OPRK1 1985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.