Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28825432 | 0.97 | THRB (0.35) | THRBACHE | |
| Iodide SCHEMBL28751658 | 0.77 | THRB (0.36) | THRB | |
| SCHEMBL11021322 | 0.77 | THRB (0.36) | THRB | |
| SCHEMBL28099313 | 0.77 | THRB (0.33) | THRB | |
| SCHEMBL8097520 | 0.76 | THRB (0.38) | THRB | |
| SCHEMBL28026597 | 0.75 | THRB (0.43) | THRB | |
| SCHEMBL9485425 | 0.74 | THRB (0.42) | THRB | |
| Hydrochloric Acid SCHEMBL11788220 | 0.73 | CA2 (0.33) | — | |
| SCHEMBL28739445 | 0.72 | ALDH1A1 (0.30) | — | |
| SCHEMBL28141524 | 0.71 | THRB (0.39) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478885-A | USING FLUOROCARBON SURFACTANT | W. R. GRACE K.K. (JP) | 1984-10-23 | — | — | US | claimed |
| US-4478885-A | USING FLUOROCARBON SURFACTANT | W. R. GRACE K.K. (JP) | 1984-10-23 | — | — | US | disclosed |