Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155335 | 0.93 | SOS1 (0.56) | HTTSMN1; SMN2FFAR1LMNASOS1 | |
| SCHEMBL11052595 | 0.92 | SOS1 (0.55) | HTTSMN1; SMN2FFAR1LMNASOS1 | |
| SCHEMBL4365042 | 0.88 | HTT (0.49) | HTTSMN1; SMN2FFAR1TDP1L3MBTL1 | |
| SCHEMBL11049593 | 0.87 | LTA4H (0.58) | HTTSMN1; SMN2LMNASOS1NR3C1 | |
| SCHEMBL7575512 | 0.84 | GAA (0.52) | HTTSMN1; SMN2TDP1CYP2C9CYP1A2 | |
| SCHEMBL11050731 | 0.83 | SMN1; SMN2 (0.45) | HTTSMN1; SMN2TDP1LMNACYP2C9 | |
| SCHEMBL12643091 | 0.81 | HTT (1.00) | HTTSMN1; SMN2FFAR1TDP1L3MBTL1 | |
| SCHEMBL8965120 | 0.81 | HTT (1.00) | HTTSMN1; SMN2FFAR1TDP1L3MBTL1 | |
| SCHEMBL11051262 | 0.81 | LTA4H (0.64) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL207124 | 0.78 | HTR6 (0.46) | SMN1; SMN2TDP1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451408-A | Process of preparing sulfonium organosulfonates | THE DOW CHEMICAL COMPANY (US) | 1984-05-29 | — | — | US | disclosed |
| US-4451409-A | Sulfonium organosulfonates | THE DOW CHEMICAL COMPANY (US) | 1984-05-29 | — | — | US | disclosed |