SCHEMBL9155335

SCHEMBL9155335

CS(=O)(=O)OS(c1ccc(Oc2ccccc2)cc1)(c1ccc(Oc2ccccc2)cc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.56
HTT P42858 4/20 0.56
LMNA P02545 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
PGR P06401 5/20 0.51
FFAR1 O14842 2/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
MMP1 P03956 1/20 0.46
MMP3 P08254 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
LTA4H P09960 2/20 0.45
PTGS2 P35354 1/20 0.45
TSHR P16473 1/20 0.44
MMP9 P14780 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11052595 0.98 SOS1 (0.55) SOS1HTTLMNASMN1; SMN2PGR
SCHEMBL11052855 0.93 HTT (0.68) SOS1HTTLMNASMN1; SMN2PGR
SCHEMBL11049593 0.93 LTA4H (0.58) SOS1HTTLMNASMN1; SMN2PGR
SCHEMBL11051262 0.87 LTA4H (0.64) HTTLMNASMN1; SMN2CA1CA2
SCHEMBL207124 0.84 HTR6 (0.46) LMNASMN1; SMN2CA1CA2CA9
SCHEMBL15063438 0.84 PKM (0.52) HTTLMNASMN1; SMN2PGRCA1
SCHEMBL7359540 0.80 SOS1 (0.64) SOS1HTTLMNASMN1; SMN2PGR
SCHEMBL8320055 0.80 CA12 (0.36) SOS1HTTLMNASMN1; SMN2PGR
SCHEMBL8316984 0.80 PPARA (0.39) SOS1HTTLMNASMN1; SMN2MMP13
SCHEMBL8320144 0.80 PPARA (0.39) SOS1HTTLMNASMN1; SMN2MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4451409-A Sulfonium organosulfonates THE DOW CHEMICAL COMPANY (US) 1984-05-29 US claimed
EP-0455083-B1 Method for making triarylsulfonium hexafluorometal or metalloid salts GEN ELECTRIC (US) 1995-03-01 EP disclosed
US-4451408-A Process of preparing sulfonium organosulfonates THE DOW CHEMICAL COMPANY (US) 1984-05-29 US disclosed
US-4451408-A Process of preparing sulfonium organosulfonates THE DOW CHEMICAL COMPANY (US) 1984-05-29 US disclosed
US-4451409-A Sulfonium organosulfonates THE DOW CHEMICAL COMPANY (US) 1984-05-29 US disclosed
US-4451409-A Sulfonium organosulfonates THE DOW CHEMICAL COMPANY (US) 1984-05-29 US disclosed