Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053174 | 0.92 | HTT (0.64) | SMN1; SMN2HTTHSD17B1HSD17B2POLB | |
| SCHEMBL31621156 | 0.90 | HTT (0.61) | SMN1; SMN2HTTHSD17B1HSD17B2POLB | |
| SCHEMBL1758239 | 0.90 | HTT (0.61) | SMN1; SMN2HTTHSD17B1HSD17B2POLB | |
| SCHEMBL5962849 | 0.89 | HSD17B1 (0.64) | SRD5A2SMN1; SMN2HTTHSD17B1HSD17B2 | |
| SCHEMBL172420 | 0.88 | CA12 (0.64) | SMN1; SMN2HTTKDM4ECA12CA1 | |
| SCHEMBL29979976 | 0.88 | CA12 (0.64) | SMN1; SMN2HTTKDM4ECA12CA1 | |
| SCHEMBL9752049 | 0.87 | HSD17B1 (0.59) | SRD5A2SMN1; SMN2HTTHSD17B1HSD17B2 | |
| SCHEMBL1758781 | 0.86 | HTT (0.75) | SRD5A2SMN1; SMN2HTTHSD17B1HSD17B2 | |
| SCHEMBL31574429 | 0.86 | HTT (0.57) | SMN1; SMN2HTTHSD17B1HSD17B2POLB | |
| Paraben SCHEMBL8851014 | 0.85 | CA12 (0.61) | SRD5A2SMN1; SMN2HTTKDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3014619-A | — | — | None | — | — | JP | disclosed |
| JP-H0314619-A | FILAMENT OF OPTICALLY ANISOTROPIC MELT-FORMING COPOLYESTER | E I DU PONT DE NEMOURS & CO | 1991-01-23 | — | — | JP | disclosed |
| EP-0069587-B1 | OPTICALLY ANISOTROPIC MELT FORMING POLYESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| EP-0069587-A1 | Optically anisotropic melt forming polyesters | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-12 | — | — | EP | disclosed |
| US-4335232-A | AROMATIC POLYESTER-POLYLACTONE COPOLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-06-15 | — | — | US | disclosed |