SCHEMBL11053329

SCHEMBL11053329

CCCCCCCCCCC=Cc1ccc2ccc(-c3ccccc3)c(O)c2n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.41
FAAH O00519 6/20 0.38
CES1 P23141 3/20 0.38
PIM1 P11309 1/20 0.38
DHFR P00374 1/20 0.37
SOAT2 O75908 1/20 0.36
SOAT1 P35610 1/20 0.36
OXER1 Q8TDS5 1/20 0.35
PTPN1 P18031 1/20 0.35
CDC25B P30305 1/20 0.35
DUSP3 P51452 1/20 0.35
GCGR P47871 1/20 0.35
CYSLTR2 Q9NS75 2/20 0.35
CYSLTR1 Q9Y271 2/20 0.35
EPHX2 P34913 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MMP2 P08253 1/20 0.34
F7 P08709 1/20 0.34
MAPT P10636 1/20 0.34
F3 P13726 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132770 0.79 MEN1 (0.52) KDM4EMAPT
SCHEMBL1132773 0.79 MEN1 (0.52) KDM4EMAPT
SCHEMBL3265939 0.75 CCR1 (0.44) LTB4RFAAHCES1DHFRKDM4E
SCHEMBL11053333 0.73 USP9X (0.46) LTB4RKDM4EMAPT
SCHEMBL29970018 0.71 KCNH2 (0.44) LTB4RFAAHCES1KDM4EMMP2
SCHEMBL22501441 0.71 KDM4E (0.50) LTB4RCYSLTR2CYSLTR1KDM4EMAPT
SCHEMBL8987310 0.70 MAPT (0.56) LTB4RFAAHCES1KDM4EMAPT
SCHEMBL8987305 0.70 MAPT (0.56) LTB4RFAAHCES1KDM4EMAPT
SCHEMBL10714703 0.69 LTB4R (0.56) LTB4RCYSLTR2CYSLTR1KDM4EMAPT
SCHEMBL11685733 0.69 PDE5A (0.38) LTB4RFAAHCES1CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4437994-A Extraction of metal ions from aqueous solution THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 1984-03-20 US disclosed
US-4012483-A Separation of cobalt from nickel in ammoniacal solutions using 8-hydroxyquinolines DEEPSEA VENTURES, INC. (US) 1977-03-15 US disclosed
US-3984520-A ION EXCHANGING DEEPSEA VENTURES, INC. (US) 1976-10-05 US disclosed
US-3930974-A TWO STAGE SELECTIVE LEACHING OF METAL VALUES FROM OCEAN FLOOR NODULE ORE DEEPSEA VENTURES, INC. (US) 1976-01-06 US disclosed