Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.69 |
| ▸ | BCHE | P06276 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968931 | 0.82 | ACHE (0.47) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5511124 | 0.82 | ACHE (0.69) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3892901 | 0.82 | ACHE (1.00) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29638891 | 0.82 | ACHE (1.00) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5506588 | 0.77 | ACHE (0.62) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29196372 | 0.75 | ACHE (0.60) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11053382 | 0.74 | ACHE (0.59) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29152960 | 0.74 | ACHE (0.62) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29206842 | 0.74 | ACHE (0.59) | ACHEBCHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL17368665 | 0.73 | ACHE (0.57) | ACHEBCHEKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495096-B2 | Processes for the production of chinazoline alkaloids | HF ARZNEIMITTELFORSCHUNG GMBH (DE) | 2009-02-24 | — | — | US | disclosed |
| EP-1590351-B1 | METHODS FOR PRODUCING QUINAZOLINE ALKALOIDS | HF ARZNEIMITTELFORSCH GMBH (DE) | 2008-09-03 | — | — | EP | disclosed |
| US-20060084669-A1 | PROCESSES FOR THE PRODUCTION OF CHINAZOLINE ALKALOIDS | HF ARZNEIMITTELFORSCHUNG GMBH (DE) | 2006-04-20 | — | — | US | disclosed |
| EP-1590351-A1 | METHODS FOR PRODUCING QUINAZOLINE ALKALOIDS | HF ARZNEIMITTELFORSCHUNG GmbH (DE) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069836-A1 | METHODS FOR PRODUCING QUINAZOLINE ALKALOIDS | HF ARZNEIMITTELFORSCHUNG GMBH (DE) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084669-A1 | PROCESSES FOR THE PRODUCTION OF CHINAZOLINE ALKALOIDS | CYP3A7, PRMT7, CYP4Z1 | ACHE 638/4885BCHE 99/4885KDM4E 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.