SCHEMBL11054907

SCHEMBL11054907

C=Cc1ccc(C(=O)Oc2ccc(NS(=O)(=O)CC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.59
LMNA P02545 2/20 0.48
KMT2A Q03164 5/20 0.46
RECQL P46063 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 2/20 0.42
GFER P55789 1/20 0.42
MEN1 O00255 1/20 0.42
AR P10275 1/20 0.42
PANK3 Q9H999 1/20 0.41
HTT P42858 1/20 0.41
F2 P00734 2/20 0.40
KLK1 P06870 2/20 0.40
PRSS1 P07477 2/20 0.40
HDAC8 Q9BY41 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049625 0.91 HPGD (0.49) HPGDLMNAKMT2ARECQLCA1
SCHEMBL11055819 0.89 AR (0.47) HPGDLMNAKMT2ARECQLCA1
SCHEMBL11050632 0.87 HPGD (0.52) HPGDLMNAKMT2ARECQLSMN1; SMN2
SCHEMBL12370871 0.81 KMT2A (0.48) LMNAKMT2ASMN1; SMN2MAPTGFER
SCHEMBL103296 0.80 KMT2A (0.54) HPGDLMNAKMT2ASMN1; SMN2MAPT
SCHEMBL16812851 0.80 KMT2A (0.54) HPGDLMNAKMT2ASMN1; SMN2MAPT
SCHEMBL11048625 0.80 PGR (0.51) LMNAKMT2AMAPTMEN1AR
SCHEMBL9568488 0.79 HPGD (0.54) HPGDLMNASMN1; SMN2MAPTAR
SCHEMBL11046505 0.79 HPGD (0.58) HPGDLMNAKMT2ARECQLCA1
SCHEMBL11054549 0.78 CA12 (0.52) KMT2ARECQLSMN1; SMN2MAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478992-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1984-10-23 US disclosed
US-4420630-A BINDERS FOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed