SCHEMBL9568488

SCHEMBL9568488

C=CC(=O)Oc1ccc(NS(=O)(=O)CC)cc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.54
THRB P10828 2/20 0.54
LMNA P02545 2/20 0.49
AR P10275 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HTT P42858 1/20 0.49
NR3C2 P08235 1/20 0.42
KIF11 P52732 1/20 0.42
MAPT P10636 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PANK3 Q9H999 1/20 0.41
TGM2 P21980 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
POLB P06746 1/20 0.40
PGR P06401 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9326040 0.84 PGR (0.51) HPGDTHRBLMNAARSMN1; SMN2
SCHEMBL11346287 0.83 HPGD (0.53) HPGDLMNAARSMN1; SMN2HTT
SCHEMBL9568699 0.82 EGFR (0.43) HPGDTHRBLMNASMN1; SMN2
SCHEMBL27743150 0.82 HPGD (0.62) HPGDLMNAARSMN1; SMN2HTT
SCHEMBL3255942 0.80 HPGD (0.55) HPGDLMNAARSMN1; SMN2HTT
SCHEMBL11054907 0.79 HPGD (0.59) HPGDLMNAARSMN1; SMN2HTT
SCHEMBL7871269 0.79 THRB (0.63) HPGDTHRBLMNASMN1; SMN2HTT
SCHEMBL6984009 0.78 HPGD (0.54) HPGDLMNAARSMN1; SMN2HTT
SCHEMBL9568569 0.78 HPGD (0.65) HPGDTHRBLMNASMN1; SMN2HTT
SCHEMBL9568588 0.77 GFER (0.60) HPGDLMNAARSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed
US-4259469-A DESIRABLE SOLUBILITY CHARACTERISTICS FOR USE IN PHOTOLITHOGRAPHY EASTMAN KODAK COMPANY (US) 1981-03-31 US disclosed