Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.42 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9925875 | 1.00 | L3MBTL1 (0.47) | L3MBTL1KLKB1TAS1R3TAS1R1LMNA | |
| SCHEMBL16994904 | 0.87 | L3MBTL1 (0.45) | L3MBTL1KLKB1TAS1R3TAS1R1LMNA | |
| SCHEMBL1912132 | 0.86 | TAOK1 (0.44) | L3MBTL1KLKB1TAS1R3TAS1R1LMNA | |
| SCHEMBL1109147 | 0.86 | TAS1R3 (0.50) | L3MBTL1TAS1R3TAS1R1LMNACTSS | |
| SCHEMBL403036 | 0.86 | TAS1R3 (0.50) | L3MBTL1TAS1R3TAS1R1LMNACTSS | |
| SCHEMBL14400913 | 0.82 | TLR2 (0.38) | KLKB1LMNACTSKALDH1A1 | |
| SCHEMBL12361270 | 0.79 | L3MBTL1 (0.41) | L3MBTL1KLKB1TAS1R3TAS1R1LMNA | |
| SCHEMBL1105505 | 0.79 | L3MBTL1 (0.41) | L3MBTL1KLKB1TAS1R3TAS1R1LMNA | |
| SCHEMBL404996 | 0.78 | TAOK1 (0.49) | L3MBTL1KLKB1TAS1R3TAS1R1LMNA | |
| SCHEMBL402742 | 0.78 | TAS1R3 (0.42) | L3MBTL1KLKB1TAS1R3TAS1R1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153843-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2012-04-10 | — | — | US | disclosed |
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-7989660-B2 | BACTERICIDE AGAINST GRAMNEGATIVE BACTERIA; RESPIARATORY SYSTEM DISORDERS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2011-08-02 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2008-10-30 | — | — | US | disclosed |
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | MRPL21, SI, PGLS | L3MBTL1 2665/4885KLKB1 2923/4885TAS1R3 4169/4885 |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | L3MBTL1 2665/4885KLKB1 2923/4885TAS1R3 4169/4885 |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | L3MBTL1 2665/4885KLKB1 2923/4885TAS1R3 4169/4885 |
| US-20100324025-A1 | Antibacterial Agents | MRPL21, SI, PGLS | L3MBTL1 2665/4885KLKB1 2923/4885TAS1R3 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.