Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057728 | 0.89 | CYP1A2 (0.49) | KMT2ACYP1A2MEN1NPSR1DRD2 | |
| SCHEMBL11049556 | 0.89 | KMT2A (0.54) | KMT2ACA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL11320569 | 0.87 | CYP1A2 (0.47) | KMT2ACYP1A2MEN1NPSR1DRD2 | |
| SCHEMBL11274193 | 0.84 | BACE1 (0.42) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL11884423 | 0.84 | BACE1 (0.46) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL11431335 | 0.82 | L3MBTL1 (0.47) | KMT2ACA1CA2CA9CYP1A2 | |
| SCHEMBL11054398 | 0.82 | KMT2A (0.45) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL11307694 | 0.82 | KMT2A (0.44) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL11090448 | 0.82 | GAA (0.43) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL11316248 | 0.82 | CYP1A2 (0.43) | KMT2ACYP1A2MEN1NPSR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073276-A1 | A method of increasing the feed efficiency of animals, and compositions for use in such a method | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1983-03-09 | — | — | EP | claimed |
| WO-1983000624-A1 | PROMOTION OF FEED EFFICIENCY IN ANIMALS | CHOU, BILLY, JA-RAY | 1983-03-03 | — | — | WO | claimed |
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4326075-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4283555-A | Amidinoureas | WILLIAM H. RORER, INC. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4219567-A | ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1980-08-26 | — | — | US | disclosed |
| US-4203920-A | ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |