Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11320569 | 0.98 | CYP1A2 (0.47) | CYP1A2NPSR1TYK2MEN1KMT2A | |
| SCHEMBL11316248 | 0.89 | CYP1A2 (0.43) | CYP1A2NPSR1TYK2MEN1KMT2A | |
| SCHEMBL7168272 | 0.89 | DRD2 (0.55) | CYP1A2NPSR1DRD2HTR2AHTR2B | |
| SCHEMBL11056409 | 0.89 | KMT2A (0.47) | CYP1A2NPSR1TYK2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10947952 | 0.88 | PKM (0.56) | CYP1A2NPSR1DRD2HTR2AHTR2B | |
| SCHEMBL10940738 | 0.86 | CACNA1C (0.56) | CYP1A2NPSR1DRD2HTR2AHTR2B | |
| SCHEMBL11431335 | 0.86 | L3MBTL1 (0.47) | CYP1A2TYK2MEN1KMT2APDK1 | |
| SCHEMBL11436778 | 0.85 | ATM (0.47) | CYP1A2NPSR1MEN1KMT2APOLB | |
| SCHEMBL11055496 | 0.85 | CXCL8 (0.46) | KMT2ALMNA | |
| SCHEMBL11429446 | 0.84 | CYP1A2 (0.39) | CYP1A2NPSR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073276-A1 | A method of increasing the feed efficiency of animals, and compositions for use in such a method | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1983-03-09 | — | — | EP | claimed |
| WO-1983000624-A1 | PROMOTION OF FEED EFFICIENCY IN ANIMALS | CHOU, BILLY, JA-RAY | 1983-03-03 | — | — | WO | claimed |
| US-4283555-A | Amidinoureas | WILLIAM H. RORER, INC. (US) | 1981-08-11 | — | — | US | claimed |
| US-4219567-A | ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1980-08-26 | — | — | US | claimed |
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | claimed |
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4326075-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4283555-A | Amidinoureas | WILLIAM H. RORER, INC. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4219567-A | ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1980-08-26 | — | — | US | disclosed |
| US-4203920-A | ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |