Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137944 | 0.90 | L3MBTL1 (0.36) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL11142917 | 0.88 | L3MBTL1 (0.35) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL11053970 | 0.83 | GAA (0.39) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL10615577 | 0.83 | HSD17B1 (0.38) | ALDH1A1ACHEHSD17B1HSD17B2POLB | |
| SCHEMBL11142932 | 0.82 | KMT2A (0.34) | MAPTALDH1A1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL11141193 | 0.82 | GAA (0.38) | MAPTALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL11055264 | 0.81 | ALDH1A1 (0.38) | MAPTALDH1A1GAA | |
| SCHEMBL11060096 | 0.77 | ALDH1A1 (0.36) | MAPTALDH1A1LMNAL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL11141378 | 0.75 | GRIN2D (0.35) | MAPTALDH1A1LMNAL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL11137243 | 0.75 | HTT (0.35) | ALDH1A1LMNAL3MBTL1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |