SCHEMBL11057181

SCHEMBL11057181

CC(C)C1=CC2=CCC3[C@@](C)(CC(OC(C[C@@]4(C)CCC[C@@]5(C)C4CC=C4C=C(C(C)C)CC[C@H]45)C4CO4)C4CO4)CCC[C@]3(C)[C@@H]2CC1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 3/20 0.66
▸ ALDH1A1 P00352 2/20 0.66
▸ LMNA P02545 2/20 0.66
▸ MAPK1 P28482 1/20 0.66
▸ HSD17B10 Q99714 3/20 0.54
▸ PDK1 Q15118 2/20 0.54
▸ PDK2 Q15119 2/20 0.54
▸ PDK3 Q15120 2/20 0.54
▸ PDK4 Q16654 2/20 0.54
▸ SLCO1B3 Q9NPD5 1/20 0.54
▸ SLCO1B1 Q9Y6L6 1/20 0.54
▸ GABRA1 P14867 1/20 0.54
▸ GABRB2 P47870 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ MAPT P10636 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11057179 1.00 ALOX15 (0.66) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL8746011 0.83 ALOX15 (0.77) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL8746013 0.83 ALOX15 (0.77) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL2189006 0.82 ALOX15 (0.66) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL2189010 0.82 ALOX15 (0.66) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL12417300 0.82 ALOX15 (0.66) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL6536466 0.82 ALOX15 (0.79) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL31037050 0.82 ALOX15 (0.79) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL29415087 0.82 ALOX15 (0.79) ALOX15ALDH1A1LMNAMAPK1HSD17B10
SCHEMBL9110079 0.82 ALOX15 (0.79) ALOX15ALDH1A1LMNAMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2904061-B1 MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME GEORGIA PACIFIC CHEMICALS LLC (US) 2019-06-19 — — EP claimed
US-9157016-B2 Modified polyphenol binder compositions and methods for making and using same GEORGIA-PACIFIC CHEMICALS LLC (US) 2015-10-13 — — US claimed
EP-2904061-A1 MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME Georgia-Pacific Chemicals LLC (US) 2015-08-12 — — EP claimed
WO-2014055463-A1 MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-10 — — WO claimed
US-10738025-B2 Modified polyphenol binder compositions and methods for making and using same GEORGIA-PACIFIC CHEMICALS LLC (US) 2020-08-11 — — US disclosed
EP-2904036-B1 METHODS FOR MAKING LIGNOCELLULOSE CONTAINING COMPOSITE PRODUCTS GEORGIA PACIFIC CHEMICALS LLC (US) 2019-09-25 — — EP disclosed
US-10421212-B2 Methods for making lignocellulose containing composite products GEORGIA-PACIFIC CHEMICALS LLC (US) 2019-09-24 — — US disclosed
EP-2970673-B1 BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME GEORGIA PACIFIC CHEMICALS LLC (US) 2019-07-03 — — EP disclosed
EP-2904061-B1 MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME GEORGIA PACIFIC CHEMICALS LLC (US) 2019-06-19 — — EP disclosed
US-20190169341-A1 BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2019-06-06 — — US disclosed
US-10227431-B2 Binder compositions and methods for making and using same GEORGIA-PACIFIC CHEMICALS LLC (US) 2019-03-12 — — US disclosed
US-20190010269-A1 BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2019-01-10 — — US disclosed
WO-2014116377-A1 COMPOSITIONS THAT INCLUDE HYDROPHOBIZING AGENTS AND STABILIZERS AND METHODS FOR MAKING AND USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-07-31 — — WO disclosed
US-20140202647-A1 COMPOSITIONS THAT INCLUDE HYDROPHOBIZING AGENTS AND STABILIZERS AND METHODS FOR MAKING AND USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-07-24 — — US disclosed
WO-2014055463-A1 MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-10 — — WO disclosed
WO-2014055462-A1 METHODS FOR MAKING LIGNOCELLULOSE CONTAINING COMPOSITE PRODUCTS GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-10 — — WO disclosed
US-RE31577-E ACRYLATE ENDCAPPED EPICHLOROHYDRIN POLYMER THE B. F. GOODRICH COMPANY (US) 1984-05-01 — — US disclosed
US-RE31469-E TERMINALLY UNSATURATED EPICHLOROHYDRIN POLYMERS THE B. F. GOODRICH COMPANY (US) 1983-12-20 — — US disclosed
US-4274994-A TOUCHNESS THE B. F. GOODRICH COMPANY (US) 1981-06-23 — — US disclosed
US-4256904-A AN EPIHALOHYDRIN POLYMER ENDCAPPED WITH ACRYLIC OR METHACRYLIC ACID; TOUGHNESS AFTER CURING THE B. F. GOODRICH COMPANY (US) 1981-03-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738025-B2 Modified polyphenol binder compositions and methods for making and using same MYB, HLCS, KDM4C ALOX15 910/4885ALDH1A1 1126/4885LMNA 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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