SCHEMBL1105722

SCHEMBL1105722

CC1c2ccccc2C=C2C=CC=CN21

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.35
CCL2 P13500 1/20 0.35
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL9228119 0.70
SCHEMBL8887214 0.69
SCHEMBL10694747 0.65 BRD4 (0.55) BRD4CCL2DRD2DRD4
SCHEMBL28177977 0.63 BRD4 (0.41) BRD4CCL2
SCHEMBL3840034 0.62
SCHEMBL8533808 0.62 BRD4 (0.47) BRD4CCL2DRD2
SCHEMBL16711477 0.61 MAOA (0.31)
SCHEMBL26205746 0.60
SCHEMBL12334141 0.60
SCHEMBL7812458 0.59 DRD2 (0.41) BRD4CCL2DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9932479-B2 Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications ENZO BIOCHEM, INC. (US) 2018-04-03 US disclosed
EP-3001199-B1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS ENZO LIFE SCIENCES INC (US) 2018-03-21 EP disclosed
US-20160280921-A1 DYES FOR ANALYSIS OF PROTEIN AGGREGATION ENZO LIFE SCIENCES, INC. (US) 2016-09-29 US disclosed
US-20160280921-A1 DYES FOR ANALYSIS OF PROTEIN AGGREGATION ENZO LIFE SCIENCES, INC. (US) 2016-09-29 US disclosed
EP-2499495-B1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES INC (US) 2016-03-30 EP disclosed
EP-2993476-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2016-03-09 EP disclosed
EP-2993477-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2016-03-09 EP disclosed
US-9250249-B2 Autophagy and phospholipidosis pathway assays ENZO BIOCHEM, INC. (US) 2016-02-02 US disclosed
US-9250249-B2 Autophagy and phospholipidosis pathway assays ENZO BIOCHEM, INC. (US) 2016-02-02 US disclosed
US-20150376411-A1 NOVEL DYES AND COMPOSITIONS, AND PROCESSES FOR USING SAME IN ANALYSIS OF PROTEIN AGGREGATION AND OTHER APPLICATIONS ENZO BIOCHEM, INC. (US) 2015-12-31 US disclosed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US disclosed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US disclosed
US-20100068752-A1 Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest ENZO LIFE SCIENCES, INC. 2010-03-18 US disclosed
US-20100041020-A1 Methods for detecting the presence, location or quantity of targets using novel dyes ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2010-02-18 US disclosed
US-20100041020-A1 Methods for detecting the presence, location or quantity of targets using novel dyes ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2010-02-18 US disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed
WO-2009014513-A1 NOVEL DYES FOR THE DETECTION OR QUANTIFICATION OF DESIRABLE TARGET MOLECULES ENZO LIFE SCIENCES, INC. (US) 2009-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits SSBP1, IMMT, DNAJA3 BRD4 2235/4885CCL2 2484/4885DRD2 4206/4885
US-20100068752-A1 Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest SSBP1, YARS1, ANXA5 BRD4 966/4885CCL2 1711/4885DRD2 3123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.