SCHEMBL11057397

SCHEMBL11057397

CCc1cc(CC)c([NH])c(CC)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.38
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
PTGS2 P35354 1/20 0.36
BACE1 P56817 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
TP53 P04637 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 2/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6378732 0.76 GABRA1 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1760666 0.74 DHFR (0.44) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL2228767 0.74 HSPA5 (0.39) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL18244029 0.74 HSPA5 (0.39) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL23838393 0.72 HSPA5 (0.38) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL6003047 0.72 HSPA5 (0.38) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL112571 0.72 HTT (0.52) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL581480 0.72 GABRA1 (0.52) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL28453455 0.72 HSPA5 (0.38) HSPA5MEN1GAAKMT2APTGS2
SCHEMBL456782 0.72 GABRA1 (0.52) HSPA5MEN1GAAKMT2APTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436641-A ANTHRAQUINONE DYES RACON INCORPORATED (US) 1984-03-13 US disclosed
US-4369120-A ANTHRAQUINONE DYES RACON INCORPORATED (US) 1983-01-18 US disclosed