Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633746 | 0.85 | GABRA1 (0.39) | GABRA1GABRB2HSPA5SIGMAR1MEN1 | |
| SCHEMBL17873619 | 0.80 | GABRA1 (0.55) | GABRA1GABRB2SIGMAR1GAAGRIN2D | |
| SCHEMBL11804523 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2HSPA5SIGMAR1 | |
| SCHEMBL469841 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2HSPA5GAAKMT2A | |
| SCHEMBL18567677 | 0.78 | SLC5A1 (0.39) | GABRA1GABRB2HSPA5SIGMAR1MEN1 | |
| SCHEMBL204196 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2MEN1KMT2ABACE1 | |
| SCHEMBL19507340 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27740004 | 0.75 | DHFR (0.35) | GABRA1GABRB2HSPA5SIGMAR1MEN1 | |
| SCHEMBL1760666 | 0.74 | DHFR (0.44) | HSPA5MEN1GAAKMT2APTGS2 | |
| SCHEMBL18244029 | 0.74 | HSPA5 (0.39) | GABRA1GABRB2HSPA5MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104327106-A | Preparation method of high-sterically-hindered arylborate compound | SHENZHEN RES INST THE HONG KONG POLYTECHNIC UNIVERSITY | 2015-02-04 | — | — | CN | claimed |
| US-20250188106-A1 | SUBSTITUTED IMIDAZO[1,5-A]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-06-12 | — | — | US | disclosed |
| CN-109734747-B | Chiral iminodiphosphate and derivatives thereof | 科勒研究有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2023172667-A2 | SUBSTITUTED IMIDAZO[1,5-a]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-09-14 | — | — | WO | disclosed |
| CN-109734747-A | Chiral imino-diacetic phosphate/ester and its derivative | 科勒研究有限公司 | 2019-05-10 | — | — | CN | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-9783561-B2 | Chiral imidodiphosphates and derivatives thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2017-10-10 | — | — | US | disclosed |
| EP-2802561-B1 | CHIRAL IMIDODIPHOSPHATES AND DERIVATIVES THEREOF | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-04 | — | — | US | disclosed |
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-04 | — | — | US | disclosed |
| CN-103180300-A | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |
| CN-101238173-A | Flame retarded styrenic foams and foam precursors | ALBEMARLE CORP (US) | 2008-08-06 | — | — | CN | disclosed |
| CN-101161764-A | Substituted pentacene red organic electroluminescent material and preparation method thereof | SHANGHAI TUOYIN DIGITAL TECHNO (CN) | 2008-04-16 | — | — | CN | disclosed |
| EP-0718291-B1 | Method for the preparation of triazole compounds | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| US-5567825-A | Method for the preparation of a triazole compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-10-22 | — | — | US | disclosed |
| EP-0718291-A1 | Method for the preparation of triazole compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | PDXK, DHPS, NQO1 | GABRA1 2456/4885GABRB2 2331/4885HSPA5 2927/4885 |
| US-20250188106-A1 | SUBSTITUTED IMIDAZO[1,5-A]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME | NDC1, NUDC, PAICS | GABRA1 2130/4885GABRB2 3248/4885HSPA5 4805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.