SCHEMBL112571

SCHEMBL112571

CCc1cc(CC)c(N)c(CC)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.52
POLB P06746 1/20 0.52
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
NOS3 P29474 2/20 0.38
NOS1 P29475 2/20 0.38
NOS2 P35228 2/20 0.38
BACE1 P56817 1/20 0.38
HSPA5 P11021 1/20 0.38
PTGS2 P35354 1/20 0.36
DHFR P00374 3/20 0.35
CA2 P00918 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824494 0.93 HTT (0.47) HTTPOLBMEN1GAAKMT2A
SCHEMBL11803532 0.87 HTT (0.42) HTTPOLBMEN1GAAKMT2A
SCHEMBL48459 0.86 HTT (0.50) HTTPOLBALDH1A1MAPTNOS3
SCHEMBL842010 0.86 HTT (0.50) HTTPOLBMEN1GAAKMT2A
SCHEMBL9853387 0.85 ALDH1A1 (0.50) HTTPOLBMEN1GAAKMT2A
SCHEMBL19972023 0.85 HTT (0.41) HTTPOLBMEN1GAAKMT2A
SCHEMBL18630175 0.85 SLC6A4 (0.42) HTTPOLBMEN1GAAKMT2A
SCHEMBL27954173 0.84 HTT (0.48) HTTPOLBALDH1A1MAPTNOS3
SCHEMBL13804214 0.84 HTT (0.39) HTTPOLBMEN1GAAKMT2A
SCHEMBL1187136 0.84 TRPA1 (0.45) HTTPOLBMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732542-B Optically pure binaphthyl NN-dioxide ligand and preparation method thereof 南京工业大学 2022-03-08 CN claimed
US-20100113791-A1 PREPARATION OF PRECURSORS OF CARBENES OF CAAC TYPE AND PREPARING SAID CARBENES THEREFROM RHODIA OPERATIONS (FR) 2010-05-06 US claimed
EP-1451160-B1 PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN ICAGEN INC (US) 2010-01-13 EP claimed
EP-2139853-A1 PROCESS FOR PREPARING PRECURSORS OF CARBENES OF CAAC TYPE AND USE THEREOF FOR PREPARING SAID CARBENES Rhodia Opérations (FR) 2010-01-06 EP claimed
WO-2008125568-A1 PROCESS FOR PREPARING PRECURSORS OF CARBENES OF CAAC TYPE AND USE THEREOF FOR PREPARING SAID CARBENES RHODIA OPERATIONS (FR) 2008-10-23 WO claimed
EP-0020138-B1 N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYLANILINE AND ITS PREPARATION; ANTIOXIDANT ADDITIVE MIXTURES INCLUDING SAID COMPOUND; THE USE OF SAID COMPOUND, SAID ADDITIVE MIXTURES AND CERTAIN ALKYLATED ANILINES AS ANTIOXIDANTS FOR ORGANIC MATERIALS; AND ORGANIC MATERIALS AFFORDED ANTIOXIDANT PROTECTION AS AFORESAID ETHYL CORPORATION (US) 1983-06-22 EP claimed
US-4269720-A N-(2-AMINO-3-ETHYL-ALPHA-METHYLBENZYLIDENE)-2,6-DIETHYL ANILINE ETHYL CORPORATION (US) 1981-05-26 US claimed
EP-0020138-A2 N-(2-amino-3-ethyl-alpha-methylbenzylidene)-2,6-diethylaniline and its preparation; antioxidant additive mixtures including said compound; the use of said compound, said additive mixtures and certain alkylated anilines as antioxidants for organic materials; and organic materials afforded antioxidant protection as aforesaid ETHYL CORPORATION (US) 1980-12-10 EP claimed
US-12404292-B2 Amino-imine metal complex and preparation method therefor and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-09-02 US disclosed
EP-4053138-B1 AMINO-IMINE METAL COMPLEX AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2025-07-16 EP disclosed
EP-4395500-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2024-07-03 EP disclosed
EP-4395499-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2024-07-03 EP disclosed
CN-118146272-A Acenaphthenyl diimine Ni (II) catalyst containing dibenzocycloheptyl and preparation method and application thereof 中国科学院化学研究所 2024-06-07 CN disclosed
EP-3912983-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-15 EP disclosed
EP-0003101-A1 Substituted N-cyclohexyl isothiourea, their preparation and their use as pesticides BAYER AG (DE) 1979-07-25 EP disclosed
US-4147804-A ANTIARRHYTHMIA AGENTS WILLIAM H. RORER, INC. (US) 1979-04-03 US disclosed
EP-0000365-A1 N-aryl-N'-alcoyl-S-alcoyl isothioureas, process for their preparation and their use against animal and vegetal pests BAYER AG (DE) 1979-01-24 EP disclosed
US-4012222-A Herbicidal compositions containing dioxolane substituted anilids and method therefor VELSICOL CHEMICAL CORPORATION (US) 1977-03-15 US disclosed
US-3983174-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-09-28 US disclosed
US-3946045-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113791-A1 PREPARATION OF PRECURSORS OF CARBENES OF CAAC TYPE AND PREPARING SAID CARBENES THEREFROM CCNC, HCCS, CYCS HTT 1670/4885POLB 3559/4885MEN1 1358/4885
US-12404292-B2 Amino-imine metal complex and preparation method therefor and application thereof WEE1, BCAT1, WASF2 HTT 4636/4885POLB 1454/4885MEN1 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.