Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 5/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2080699 | 0.75 | GRK5 (0.68) | ITGA4ITGB7GRK5TYRO3DYRK1B | |
| SCHEMBL11713352 | 0.72 | KDM4E (0.54) | ITGA4ITGB7GRK5TYRO3DYRK1B | |
| SCHEMBL18481366 | 0.66 | ITGA4 (0.55) | ITGA4ITGB7GRK5TYRO3DYRK1B | |
| SCHEMBL18481365 | 0.66 | ITGA4 (0.51) | ITGA4ITGB7GRK5TYRO3DYRK1B | |
| SCHEMBL11555543 | 0.65 | ITGA4 (0.47) | ITGA4ITGB7GRK5TYRO3DYRK1B | |
| SCHEMBL16280099 | 0.64 | MGLL (0.62) | GRK5TYRO3DYRK1BMEN1KMT2A | |
| SCHEMBL11182628 | 0.64 | MGLL (0.62) | GRK5TYRO3DYRK1BMEN1KMT2A | |
| SCHEMBL125016 | 0.63 | MEN1 (0.68) | MAPTMEN1KMT2AL3MBTL1PKM | |
| SCHEMBL9679081 | 0.61 | KDM4E (0.44) | ITGA4ITGB7GRK5TYRO3DYRK1B | |
| SCHEMBL9677882 | 0.61 | KDM4E (0.51) | ITGA4ITGB7GRK5TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452806-A | Treating diabetic complications with 5-(substituted phenyl)hydantoins | PFIZER INC. (US) | 1984-06-05 | — | — | US | disclosed |