Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 5/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555543 | 0.80 | ITGA4 (0.47) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL2080699 | 0.79 | GRK5 (0.68) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL11798986 | 0.73 | ITGA4 (0.43) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL11798981 | 0.73 | ITGA4 (0.43) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL11093339 | 0.71 | ITGA4 (0.43) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL11562341 | 0.70 | ELANE (0.45) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL12220387 | 0.70 | ALDH1A1 (0.53) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18481366 | 0.69 | ITGA4 (0.55) | ITGA4ITGB7MAPTMEN1KMT2A | |
| SCHEMBL12220517 | 0.69 | ALDH1A1 (0.45) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11713352 | 0.68 | KDM4E (0.54) | ITGA4ITGB7MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10265318-B2 | Medicinal drug with activity against gram positive bacteria, mycobacteria and fungi | LEVINA ELIZABETH (US) | 2019-04-23 | — | — | US | disclosed |
| US-20170035758-A1 | Medicinal Drug with Activity against Gram Positive Bacteria, Mycobacteria and Fungi | LEVINA ELIZABETH (US) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10265318-B2 | Medicinal drug with activity against gram positive bacteria, mycobacteria and fungi | HRH4, HRH1, HRH2 | ITGA4 3041/4885ITGB7 3595/4885MAPT 589/4885 |
| US-20170035758-A1 | Medicinal Drug with Activity against Gram Positive Bacteria, Mycobacteria and Fungi | HRH4, HRH1, HRH2 | ITGA4 3041/4885ITGB7 3595/4885MAPT 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.