Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3915979 | 0.99 | KDM4E (0.80) | KDM4EPOLBRECQLMAPTHTT | |
| Iodide SCHEMBL2057098 | 0.99 | KDM4E (0.75) | KDM4EPOLBRECQLMAPTHTT | |
| SCHEMBL15419914 | 0.99 | KDM4E (0.79) | KDM4EPOLBRECQLMAPTHTT | |
| SCHEMBL16663887 | 0.94 | KDM4E (0.81) | KDM4EPOLBRECQLMAPTHTT | |
| SCHEMBL8022993 | 0.88 | KDM4E (0.97) | KDM4EPOLBRECQLMAPTHTT | |
| Iodide SCHEMBL29210094 | 0.87 | KDM4E (0.94) | KDM4EPOLBRECQLMAPTHTT | |
| Bromide SCHEMBL8512189 | 0.87 | KDM4E (1.00) | KDM4EPOLBRECQLMAPTHTT | |
| SCHEMBL13686278 | 0.87 | KDM4E (0.62) | KDM4EPOLBRECQLBCHEACHE | |
| SCHEMBL13645489 | 0.85 | KDM4E (0.64) | KDM4EPOLBRECQLMAPTHTT | |
| SCHEMBL7069818 | 0.84 | KDM4E (0.54) | KDM4EPOLBRECQLMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850382-B1 | Unsymmetrical cyanine dyes and their application | Ying, Laiqiang (US) | 2017-12-26 | — | — | US | disclosed |
| US-9850382-B1 | Unsymmetrical cyanine dyes and their application | Ying, Laiqiang (US) | 2017-12-26 | — | — | US | disclosed |
| US-9670476-B2 | Enzyme substrate comprising a functional dye and associated technology and methods | BIOTIUM, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160237421-A9 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-8846952-B2 | Detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20140273151-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-8778627-B2 | Enzyme substrate comprising a functional dye and associated technology and methods | BIOTIUM, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8759526-B2 | Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules | ENZO LIFE SCIENCES, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8586325-B2 | Enzyme substrate comprising a functional dye and associated technology and methods | BIOTIUM, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-8574881-B2 | Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-7569695-B2 | Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization | ENZO LIFE SCIENCES, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-20090148386-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. | 2009-06-11 | — | — | US | disclosed |
| WO-2007100392-A2 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| US-7166715-B2 | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds | APPLERA CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-20050233360-A1 | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes | PROLIGO, LLC (US) | 2005-10-20 | — | — | US | disclosed |
| US-6902900-B2 | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes | PROLICO, LLC (US) | 2005-06-07 | — | — | US | disclosed |
| EP-1442142-A2 | NUCLEIC ACID PROBES AND METHODS TO DETECT AND/OR QUANTIFY NUCLEIC ACID ANALYTES | Proligo LLC (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20030143591-A1 | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes | PROLIGO, LLC (US) | 2003-07-31 | — | — | US | disclosed |
| EP-1318177-A2 | Compound, in particular marker-dye, based on polymethines | Dyomics GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2003043402-A2 | NUCLEIC ACID PROBES AND METHODS TO DETECT AND/OR QUANTIFY NUCLEIC ACID ANALYTES | PROLIGO LLC (US) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030143591-A1 | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes | HLA-C, HLA-B, SLC43A3 | KDM4E 4870/4885POLB 151/4885RECQL 1747/4885 |
| US-20050233360-A1 | Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes | HLA-C, HLA-B, SLC43A3 | KDM4E 4870/4885POLB 151/4885RECQL 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.