Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3916333 | 0.99 | KDM4E (0.56) | KDM4EPOLBLMNAALDH1A1TSHR | |
| SCHEMBL6262227 | 0.84 | KDM4E (0.49) | KDM4EPOLBLMNAALDH1A1TSHR | |
| SCHEMBL1105809 | 0.84 | KDM4E (0.77) | KDM4EPOLBRECQLKMT2AMAPT | |
| Iodide SCHEMBL2057098 | 0.83 | KDM4E (0.75) | KDM4EPOLBLMNAALDH1A1RECQL | |
| Bromide SCHEMBL3915979 | 0.83 | KDM4E (0.80) | KDM4EPOLBLMNAALDH1A1RECQL | |
| SCHEMBL15419914 | 0.82 | KDM4E (0.79) | KDM4EPOLBALDH1A1TSHRRECQL | |
| SCHEMBL16663887 | 0.78 | KDM4E (0.81) | KDM4EPOLBLMNAALDH1A1TSHR | |
| SCHEMBL7069821 | 0.75 | KDM4E (0.52) | KDM4EPOLBALDH1A1TSHRRECQL | |
| Bromide SCHEMBL3916334 | 0.74 | POLB (0.54) | KDM4EPOLBALDH1A1RECQLMEN1 | |
| Hydrochloric Acid SCHEMBL11599422 | 0.72 | KDM4E (0.56) | KDM4EPOLBLMNAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318177-A2 | Compound, in particular marker-dye, based on polymethines | Dyomics GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |