Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.58 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.54 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HK1 | P19367 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560781 | 0.92 | IDO1 (0.60) | FGFR1FGFR2FGFR4FGFR3IDO1 | |
| SCHEMBL11793576 | 0.84 | FGFR1 (0.69) | FGFR1FGFR2FGFR4FGFR3KMT2A | |
| SCHEMBL11062611 | 0.83 | IDO1 (0.60) | FGFR1FGFR2FGFR4FGFR3IDO1 | |
| SCHEMBL30304915 | 0.77 | APAF1 (0.62) | FGFR1FGFR2FGFR4FGFR3KMT2A | |
| SCHEMBL2901813 | 0.75 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3KMT2A | |
| SCHEMBL29834814 | 0.75 | APAF1 (0.60) | FGFR1FGFR2FGFR4FGFR3KMT2A | |
| SCHEMBL28758923 | 0.75 | APAF1 (0.60) | FGFR1FGFR2FGFR4FGFR3KMT2A | |
| SCHEMBL30179153 | 0.75 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3KMT2A | |
| SCHEMBL229681 | 0.75 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3KMT2A | |
| Dichlon SCHEMBL28269079 | 0.74 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463142-A | Photocrosslinkable polymers with side groups derived from indenone and the preparation and use of these polymers | CIBA-GEIGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| US-4399259-A | ACRYLIC ESTER HOMO- AND COPOLYMERS; KETONE RESINS; BROMO- AND CHLOROPOLYMERS; PHOTORESISTS | CIBA-GEIGY CORPORATION (US) | 1983-08-16 | — | — | US | disclosed |
| US-4323701-A | FROM DIHALOGENOMALEIC ANHYDRIDES OR ACYL HALIDE AND AN AROMATIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |