SCHEMBL30179153

SCHEMBL30179153

NC1=C(C(=O)O)C(=O)c2ccccc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 3/20 0.58
FGFR2 P21802 3/20 0.58
FGFR4 P22455 3/20 0.58
FGFR3 P22607 3/20 0.58
ALDH1A1 P00352 7/20 0.50
MAPT P10636 5/20 0.50
NPC1 O15118 2/20 0.50
POLB P06746 2/20 0.50
PKM P14618 2/20 0.50
SRC P12931 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
NSD2 O96028 1/20 0.50
RAB9A P51151 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
LMNA P02545 4/20 0.49
NPSR1 Q6W5P4 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
XBP1 P17861 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229681 1.00 FGFR1 (0.58) FGFR1FGFR2FGFR4FGFR3ALDH1A1
Naphthoquinone SCHEMBL6058878 0.91 FGFR1 (0.50) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL11793576 0.84 FGFR1 (0.69) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL27816218 0.84 ALDH1A1 (0.64) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL29630310 0.77 FGFR1 (0.61) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL28948278 0.77 FGFR1 (0.61) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL30304915 0.77 APAF1 (0.62) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL29563346 0.77 RAB9A (0.68) ALDH1A1MAPTNPC1POLBPKM
SCHEMBL1510327 0.77 RAB9A (0.68) ALDH1A1MAPTNPC1POLBPKM
SCHEMBL16681684 0.76 FGFR1 (0.44) FGFR1FGFR2FGFR4FGFR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117156872-A Perovskite solar cell with modified interface and preparation method thereof 中国科学院广州能源研究所 2023-12-01 CN claimed
CN-109803668-B Composition for inhibiting the reduction of Lactobacillus in the intestinal tract 株式会社明治 2024-01-09 CN disclosed
CN-117156872-A Perovskite solar cell with modified interface and preparation method thereof 中国科学院广州能源研究所 2023-12-01 CN disclosed
CN-116941078-A Fat decomposition device, fat decomposition method, and power generation method 株式会社村田制作所 2023-10-24 CN disclosed
WO-2022230464-A1 LIPOLYSIS DEVICE, LIPOLYSIS METHOD, AND ELECTRIC POWER GENERATION METHOD 株式会社村田製作所 2022-11-03 WO disclosed