SCHEMBL229681

SCHEMBL229681

NC1=C(C(=O)O)C(=O)c2ccccc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 3/20 0.58
FGFR2 P21802 3/20 0.58
FGFR4 P22455 3/20 0.58
FGFR3 P22607 3/20 0.58
ALDH1A1 P00352 7/20 0.50
MAPT P10636 5/20 0.50
NPC1 O15118 2/20 0.50
POLB P06746 2/20 0.50
PKM P14618 2/20 0.50
SRC P12931 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
NSD2 O96028 1/20 0.50
RAB9A P51151 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
LMNA P02545 4/20 0.49
NPSR1 Q6W5P4 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
XBP1 P17861 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30179153 1.00 FGFR1 (0.58) FGFR1FGFR2FGFR4FGFR3ALDH1A1
Naphthoquinone SCHEMBL6058878 0.91 FGFR1 (0.50) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL11793576 0.84 FGFR1 (0.69) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL27816218 0.84 ALDH1A1 (0.64) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL29630310 0.77 FGFR1 (0.61) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL28948278 0.77 FGFR1 (0.61) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL30304915 0.77 APAF1 (0.62) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL29563346 0.77 RAB9A (0.68) ALDH1A1MAPTNPC1POLBPKM
SCHEMBL1510327 0.77 RAB9A (0.68) ALDH1A1MAPTNPC1POLBPKM
SCHEMBL16681684 0.76 FGFR1 (0.44) FGFR1FGFR2FGFR4FGFR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022172173-A1 BIOCHEMICAL ELECTRICAL GENERATOR WITH ELECTRONIC TRANSFER MEDIATOR SINOPOLI PAOLO (IT) 2022-08-18 WO claimed
US-8093301-B2 Anti-allergic agent MEIJI CO., LTD. (JP) 2012-01-10 US claimed
CN-101247800-B Antiallergic agent MEIJI DAIRIES CORP 2011-04-27 CN claimed
EP-1946752-B1 ANTI-ALLERGIC AGENT MEIJI DAIRIES CORP (JP) 2011-04-20 EP claimed
CN-1802434-B Immobilization support, process for producing the same, electrode, process for producing the same, electrode reaction utilizing apparatus and process for producing the same SONY CORP 2011-03-23 CN claimed
EP-1630227-B1 IMMOBILIZATION SUPPORT, PROCESS FOR PRODUCING THE SAME, ELECTRODE, PROCESS FOR PRODUCING THE SAME, ELECTRODE REACTION UTILIZING APPARATUS AND PROCESS FOR PRODUCING THE SAME SONY CORP (JP) 2010-08-18 EP claimed
US-7709537-B1 Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials MEIJI DAIRIESE CORPORATION (JP) 2010-05-04 US claimed
US-20090281187-A1 ANTI-ALLERGIC AGENT MEIJI DAIRIES CORP (JP) 2009-11-12 US claimed
US-7520970-B2 Immobilization support, process for producing the same, electrode, process for producing the same, electrode reaction utilizing apparatus and process for producing the same SONY CORPORATION (JP) 2009-04-21 US claimed
CN-101247800-A Antiallergic agent MEIJI DAIRIES CORP (JP) 2008-08-20 CN claimed
EP-1946752-A1 ANTI-ALLERGIC AGENT Meiji Dairies Corporation (JP) 2008-07-23 EP claimed
EP-1230920-B1 USE OF FOOD MATERIALS IN PREVENTING AND AMELIORATING METABOLIC BONE DISEASES MEIJI DAIRIES CORP (JP) 2006-07-19 EP claimed
CN-1382043-A Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials MEIJI MILK PROD CO LTD (JP) 2002-11-27 CN claimed
EP-1230920-A1 FOOD MATERIALS USEFUL IN PREVENTING AND AMELIORATING METABOLIC BONE DISEASES AND PREVENTIVES/REMEDIES FOR METABOLIC BONE DISEASES COMPRISING THESE MATERIALS Meiji Dairies Corporation (JP) 2002-08-14 EP claimed
JP-10036328-A None JP disclosed
JP-7289273-A None JP disclosed
JP-8098677-A None JP disclosed
JP-H0898677-A COMPOSITION FOR PROMOTING PROLIFERATION OF BIFIDOBACTERIUM MEIJI MILK PROD CO LTD 1996-04-16 JP disclosed
JP-H07289273-A NAPHTHOQUINONE DERIVATIVE MEIJI MILK PROD CO LTD 1995-11-07 JP disclosed
JP-H00898677-A 0001-01-01 JP disclosed