Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | APEX1 | P27695 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940420 | 0.79 | AKR1B1 (0.52) | CA2GAANPSR1PRKCETDP1 | |
| SCHEMBL9313082 | 0.77 | MEN1 (0.37) | CA2PRKCETDP1RECQLMAPT | |
| SCHEMBL6789908 | 0.77 | CA2 (0.45) | CA2GAANPSR1TDP1MAPT | |
| Lithium Ion SCHEMBL30940418 | 0.76 | PRKCE (0.38) | CA2GAAPRKCETDP1RECQL | |
| Potassium Ion SCHEMBL30940405 | 0.76 | NR4A1 (0.41) | CA2GAAPRKCETDP1RECQL | |
| SCHEMBL30940454 | 0.76 | PRKCE (0.38) | CA2GAAPRKCETDP1RECQL | |
| SCHEMBL3397478 | 0.75 | ALOX15 (0.48) | CA2PRKCETDP1RECQLMAPT | |
| SCHEMBL6217976 | 0.74 | CA2 (0.52) | CA2GAATDP1RECQLMAPT | |
| SCHEMBL31485520 | 0.72 | CCR6 (0.36) | CA2GAANPSR1TDP1RECQL | |
| SCHEMBL14579847 | 0.70 | MEN1 (0.40) | CA2GAANPSR1TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448730-A | ANTITUMOR AGENTS | RIET BARTHOLOMEUS VAN T | 1984-05-15 | — | — | US | disclosed |