Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068350 | 0.82 | PDE3B (0.41) | PDE3BPDE3AKMT2AKCNH2 | |
| SCHEMBL11278612 | 0.73 | LMNA (0.46) | KCNH2 | |
| SCHEMBL11071895 | 0.73 | PDE3B (0.40) | SLC6A2SLC6A4SLC6A3PDE3BPDE3A | |
| SCHEMBL12090742 | 0.69 | CYP19A1 (0.48) | KMT2AKCNH2 | |
| SCHEMBL11058886 | 0.69 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11065352 | 0.69 | KMT2A (0.41) | PDE3BPDE3AKMT2A | |
| SCHEMBL11069955 | 0.69 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL11067771 | 0.68 | PDE3B (0.41) | PDE3BPDE3AKMT2AKCNH2 | |
| SCHEMBL11061370 | 0.68 | PDE3B (0.35) | PDE3BPDE3AKCNH2 | |
| SCHEMBL6588791 | 0.67 | CCR1 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |