Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062853 | 0.79 | PDE3B (0.61) | KMT2AALDH1A1TSHRMAPK1PDE3B | |
| SCHEMBL11067771 | 0.77 | PDE3B (0.41) | KMT2APDE3BPDE3AMEN1 | |
| SCHEMBL11068350 | 0.77 | PDE3B (0.41) | KMT2APDE3BPDE3AMEN1 | |
| SCHEMBL11071895 | 0.74 | PDE3B (0.40) | KMT2AMAPTGAAPDE3BPDE3A | |
| SCHEMBL11062162 | 0.74 | TRPM8 (0.44) | KMT2ATSHRMAPK1PDE3BPDE3A | |
| SCHEMBL11065412 | 0.73 | PDE3B (0.59) | KMT2AALDH1A1TSHRMAPK1PDE3B | |
| SCHEMBL11058886 | 0.73 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11069703 | 0.72 | PDE3B (0.59) | KMT2AALDH1A1TSHRMAPK1PDE3B | |
| SCHEMBL11065776 | 0.72 | ADRB2 (0.40) | TSHRMAPK1PDE3BPDE3AHPGD | |
| SCHEMBL11061370 | 0.71 | PDE3B (0.35) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |