Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067771 | 0.83 | PDE3B (0.41) | PDE3BPDE3AMEN1KMT2AMAOA | |
| SCHEMBL11058886 | 0.78 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11069955 | 0.78 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL11071107 | 0.75 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL11065352 | 0.74 | KMT2A (0.41) | PDE3BPDE3AMEN1KMT2AGAA | |
| SCHEMBL11068350 | 0.73 | PDE3B (0.41) | PDE3BPDE3AMEN1KMT2ACYP11B2 | |
| SCHEMBL11062162 | 0.73 | TRPM8 (0.44) | PDE3BPDE3AMEN1KMT2AMAOA | |
| SCHEMBL11058649 | 0.73 | USP30 (0.39) | PDE3BPDE3AKMT2ASLC6A2SLC6A4 | |
| SCHEMBL12090742 | 0.71 | CYP19A1 (0.48) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11278612 | 0.71 | LMNA (0.46) | MAOAMAOBCCR1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |