Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 10/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071895 | 0.83 | PDE3B (0.40) | PDE3BPDE3AMEN1KMT2ACCR1 | |
| SCHEMBL11058886 | 0.81 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11069955 | 0.80 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL11068350 | 0.78 | PDE3B (0.41) | PDE3BPDE3AS1PR5MEN1KMT2A | |
| SCHEMBL11071107 | 0.78 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL11065352 | 0.77 | KMT2A (0.41) | PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL11313435 | 0.75 | ATM (0.41) | PDE3BPDE3AL3MBTL1MEN1KMT2A | |
| SCHEMBL11065568 | 0.75 | ADRB2 (0.42) | PDE3BPDE3AL3MBTL1KCNH2DRD2 | |
| SCHEMBL11062162 | 0.73 | TRPM8 (0.44) | PDE3BPDE3AMEN1KMT2ACCR1 | |
| SCHEMBL12090742 | 0.72 | CYP19A1 (0.48) | MEN1KMT2ACCR1KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |