SCHEMBL11058698

SCHEMBL11058698

CCC1=CC(=O)CC(C)C1CC=C(C)C

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
PKM P14618 1/20 0.31
ABCB11 O95342 1/20 0.31
PTGS1 P23219 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058706 0.81 ALDH1A1 (0.33) ALDH1A1LMNACYP1A2CYP3A4CYP2C9
SCHEMBL11227201 0.69
SCHEMBL30876312 0.67
SCHEMBL11058198 0.67 NFKB1 (0.33) ALDH1A1LMNAPKMABCB11PTGS1
SCHEMBL11061540 0.66
SCHEMBL11085136 0.64
SCHEMBL11085142 0.64
SCHEMBL11062003 0.63 ABCB11 (0.34) ALDH1A1LMNASMN1; SMN2PKMABCB11
SCHEMBL18855852 0.63
SCHEMBL21616444 0.62 ALDH1A1 (0.33) ALDH1A1LMNACYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4432378-A ORGANOLEPTIC; TOBACCO; FOODS; DETERGENTS; COSMETICS FRITZSCHE, DODGE & OLCOTT, INC. (US) 1984-02-21 US disclosed
US-4326996-A FOR PERFUMES FRITZSCHE DODGE & OLCOTT INC. (US) 1982-04-27 US disclosed