Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL25260199 | 0.96 | LMNA (0.48) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL25262539 | 0.96 | LMNA (0.48) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL15662978 | 0.94 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL2266457 | 0.88 | LMNA (0.38) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL2268824 | 0.88 | LMNA (0.38) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL25302907 | 0.87 | ALDH1A1 (0.41) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL7757207 | 0.87 | OPRM1 (0.48) | LMNATSHRFAAHCNR1CNR2 | |
| SCHEMBL5012572 | 0.87 | OPRM1 (0.48) | LMNATSHRFAAHCNR1CNR2 | |
| SCHEMBL6420889 | 0.87 | OPRM1 (0.48) | LMNATSHRFAAHCNR1CNR2 | |
| SCHEMBL1932307 | 0.87 | OPRM1 (0.48) | LMNATSHRFAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486350-A | REDUCTION OF SULFOCHLORIDE WITH REDUCING AGENT IN PRESENCE OF HYDRIODIC ACID | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-12-04 | — | — | US | disclosed |