Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071377 | 0.90 | — | — | |
| SCHEMBL11064059 | 0.83 | HRH3 (0.46) | — | |
| SCHEMBL11062767 | 0.80 | MAOA (0.66) | DRD2DRD4DRD3 | |
| SCHEMBL11063730 | 0.79 | TACR2 (0.43) | — | |
| SCHEMBL10571216 | 0.78 | DRD2 (0.61) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL11070987 | 0.78 | DRD2 (0.60) | DRD2DRD4DRD3 | |
| Oxalic Acid SCHEMBL11069052 | 0.77 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL11068167 | 0.77 | TSHR (0.47) | — | |
| SCHEMBL11095714 | 0.77 | CHRM1 (0.62) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL11073559 | 0.76 | MEN1 (0.47) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |