Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063730 | 0.95 | TACR2 (0.43) | HRH3TACR2TACR1TACR3HTR7 | |
| SCHEMBL11070987 | 0.83 | DRD2 (0.60) | HTR7 | |
| SCHEMBL11060233 | 0.83 | CHRM1 (0.50) | — | |
| SCHEMBL11071377 | 0.83 | — | — | |
| SCHEMBL11062767 | 0.81 | MAOA (0.66) | — | |
| SCHEMBL11064993 | 0.80 | HTR7 (0.51) | HRH3TACR2TACR1TACR3HTR7 | |
| SCHEMBL10573223 | 0.79 | DRD3 (0.60) | HRH3HTR7 | |
| SCHEMBL11065756 | 0.79 | KDM1A (0.55) | HTR7 | |
| SCHEMBL11064495 | 0.76 | DRD2 (0.56) | HRH3HTR7 | |
| SCHEMBL5904112 | 0.76 | HRH3 (0.53) | HRH3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |