Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071377 | 0.87 | — | — | |
| SCHEMBL10578077 | 0.82 | HTR7 (0.63) | ALDH1A1L3MBTL1HTR7LMNAADRB3 | |
| SCHEMBL11072960 | 0.81 | KCNH2 (0.51) | HTR7LMNAGAAPKM | |
| SCHEMBL11068145 | 0.80 | KCNH2 (0.49) | — | |
| SCHEMBL11066226 | 0.80 | DRD4 (0.62) | TSHRPOLBGAA | |
| SCHEMBL11060233 | 0.77 | CHRM1 (0.50) | — | |
| SCHEMBL10568516 | 0.74 | HTR7 (0.50) | ALDH1A1HTR7LMNA | |
| SCHEMBL10570453 | 0.73 | MAPT (0.60) | HSD17B10ALDH1A1HTR7LMNAADRB3 | |
| SCHEMBL11063819 | 0.73 | CHRM2 (0.46) | — | |
| SCHEMBL11065197 | 0.73 | DRD4 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |