Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059553 | 0.81 | ALDH1A1 (0.50) | HSD17B10CYP3A4ALDH1A1ESR1ESR2 | |
| SCHEMBL16500490 | 0.75 | ESR1 (0.49) | NR4A2HSD17B10TSHRALDH1A1ESR1 | |
| SCHEMBL7608692 | 0.74 | NR4A2 (0.52) | NR4A2ALDH1A1PDGFRBPDGFRARXFP1 | |
| SCHEMBL17434591 | 0.72 | HSD17B10 (0.41) | HSD17B10CYP3A4ALDH1A1ESR1ESR2 | |
| SCHEMBL31081799 | 0.70 | ALOX15 (0.42) | NR4A2HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL11059176 | 0.68 | CYP2A6 (0.42) | HSD17B10TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL14720338 | 0.67 | NR4A2 (0.50) | NR4A2HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL29276998 | 0.67 | ESR1 (0.61) | NR4A2HSD17B10TSHRCYP3A4ALDH1A1 | |
| SCHEMBL17423219 | 0.66 | MAPT (0.65) | NR4A2ALDH1A1TDP1ESR1ESR2 | |
| SCHEMBL28208080 | 0.66 | NR4A2 (0.44) | NR4A2ALDH1A1PDGFRBPDGFRARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452792-A | Acridine substituted phosphorus compounds and their insecticidal use | VELSICOL CHEMICAL CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |