Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308273 | 0.82 | HTR6 (0.40) | SMN1; SMN2NPC1MAPTRAB9ANFKB1 | |
| SCHEMBL27596873 | 0.80 | HTR6 (0.39) | SMN1; SMN2NPC1MAPTRAB9ANFKB1 | |
| Lithium SCHEMBL3684629 | 0.80 | HTR6 (0.39) | SMN1; SMN2NPC1MAPTRAB9ANFKB1 | |
| SCHEMBL3684627 | 0.80 | HTR6 (0.39) | SMN1; SMN2NPC1MAPTRAB9ANFKB1 | |
| SCHEMBL476571 | 0.75 | HTR6 (0.36) | SMN1; SMN2HTR6CHEK1DAPK3LTK | |
| SCHEMBL7549356 | 0.75 | HTR6 (0.36) | HTR6LMNACA1CA2CES1 | |
| SCHEMBL28209545 | 0.75 | HTR6 (0.36) | HTR6CA1CA2CES1MAOA | |
| SCHEMBL396140 | 0.75 | MAOA (0.50) | SMN1; SMN2NPC1MAPTRAB9ANFKB1 | |
| SCHEMBL9798521 | 0.72 | DCUN1D1 (0.30) | DCUN1D1 | |
| SCHEMBL9254888 | 0.69 | SRD5A2 (0.38) | SMN1; SMN2RAB9AHTR6LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477380-A | Oxidation process of reactive aromatics with reactivation of the catalyst using potassium permanganate | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1984-10-16 | — | — | US | disclosed |
| US-4071405-A | BETA- OR GAMMA-AMINO ACIDS, METHIONINASE | AJINOMOTO CO., INC. (JA) | 1978-01-31 | — | — | US | disclosed |