SCHEMBL476571

SCHEMBL476571

OC1=CCc2ccccc2C1=S

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.36
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
RNASEH1 O60930 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DCUN1D1 Q96GG9 1/20 0.32
CES1 P23141 1/20 0.31
MAOA P21397 1/20 0.31
BCL2 P10415 1/20 0.30
MCL1 Q07820 1/20 0.30
CHEK1 O14757 1/20 0.30
DAPK3 O43293 1/20 0.30
LTK P29376 1/20 0.30
MAPK8 P45983 1/20 0.30
CSNK1A1 P48729 1/20 0.30
CDK8 P49336 1/20 0.30
LIMK1 P53667 1/20 0.30
CDK5 Q00535 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276263 0.82 HTR6 (0.40) HTR6CYP1A2CYP3A4RNASEH1LMNA
SCHEMBL2566227 0.75 CES1 (0.50) CYP1A2CYP3A4RNASEH1CES1MAOA
SCHEMBL11060593 0.75 SMN1; SMN2 (0.36) HTR6CYP3A4LMNASMN1; SMN2DCUN1D1
SCHEMBL6624132 0.75 HTR6 (0.43) HTR6CYP1A2CYP3A4LMNASMN1; SMN2
SCHEMBL9254888 0.73 SRD5A2 (0.38) HTR6LMNASMN1; SMN2CES1MAOA
SCHEMBL6525907 0.71 HTR6 (0.33) HTR6RNASEH1
SCHEMBL11452962 0.69 ALDH1A1 (0.34)
SCHEMBL28352725 0.69 HSD17B10 (0.50) CYP1A2CYP3A4LMNACES1MCL1
SCHEMBL4448883 0.69 HTR6 (0.40) HTR6LMNASMN1; SMN2CES1MAOA
SCHEMBL29073266 0.69 MAOA (0.46) CYP1A2CYP3A4RNASEH1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 563 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265499-B Reduction dehalogenation method of organic halogenated compound 华中科技大学 2020-10-02 CN claimed
US-9694243-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2017-07-04 US claimed
CN-106281202-A A kind of binding agent for polyurethane screen and using method 安徽龙川橡塑科技有限公司 2017-01-04 CN claimed
US-9526949-B2 Golf ball DUNLOP SPORTS CO., LTD. (JP) 2016-12-27 US claimed
WO-2016161033-A1 METHODS FOR MAKING OLIGOMERIC ACIDS AND ROSIN OIL FROM CRUDE TALL OIL GEORGIA-PACIFIC CHEMICALS LLC (US) 2016-10-06 WO claimed
US-9457234-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2016-10-04 US claimed
CN-105358541-A Formation of chiral 4-chromanone using chiral pyrrolidine in the presence of phenol or thiophenol DSM IP ASSETS BV 2016-02-24 CN claimed
US-20150273278-A1 GOLF BALL DUNLOP SPORTS CO., LTD. (JP) 2015-10-01 US claimed
US-20150065270-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-03-05 US claimed
US-20140100058-A1 GOLF BALL Dunlop Sprorts Co., Ltd. (JP) 2014-04-10 US claimed
CN-101743210-B Metallic surface enhancement ENTHONE 2013-04-17 CN claimed
CN-101743210-A Metal surface enhanced ENTHONE 2010-06-16 CN claimed
US-7119127-B2 Golf balls containing cis-to-trans converted polybutadiene and methods for making same ACUSHNET COMPANY (US) 2006-10-10 US claimed
US-20050215729-A1 Golf balls containing cis-to-trans converted polybutadiene and methods for making same JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-09-29 US claimed
US-5656680-A AN ALKYLBENZENESULFONIC ACID; DOES NOT ADVERSELY AFFECT THE ADHESION, TACK, MODULUS AND TENSILE STRENGTH OF RUBBER TECHNICAL PROCESSING, INC. (US) 1997-08-12 US claimed
EP-0469778-B1 Method and composition for improving processability of rubber and plastics TECHNICAL PROCESSING INC (US) 1997-06-11 EP claimed
US-5155189-A Derived from repeating units of acrylic and/or methacrylic ester polymers THE B. F. GOODRICH COMPANY (US) 1992-10-13 US claimed
EP-0469778-A1 Method and composition for improving processability of rubber and plastics TECHNICAL PROCESSING, INC. (US) 1992-02-05 EP claimed
EP-0261079-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1991-10-16 EP claimed
US-4035424-A Method of preparing symmetrical diarylsulphides DERYAGINA ELEONORA NIKOLAEVNA 1977-07-12 US claimed