SCHEMBL11060656

SCHEMBL11060656

COc1cc(-c2ccc(C)cc2)c(OC)cc1[N+]#N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.38
SYK P43405 1/20 0.37
ACHE P22303 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
AR P10275 2/20 0.36
MEN1 O00255 1/20 0.36
PRNP P04156 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDGFRB P09619 1/20 0.36
PDGFRA P16234 1/20 0.36
MAOB P27338 1/20 0.35
GUSB P08236 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236398 1.00 BACE1 (0.38) BACE1SYKACHEALDH1A1HPGD
Trifluoromethanesulfonic Acid SCHEMBL11064376 0.85 KCNH2 (0.36) ALDH1A1KMT2AMEN1
SCHEMBL8988230 0.80 ADORA3 (0.41) SYKALDH1A1HPGDKMT2ANPC1
Hydrochloric Acid SCHEMBL3804779 0.78 CYP1A1 (0.54) SYKALDH1A1KMT2APDGFRBPDGFRA
SCHEMBL17251283 0.76 ACHE (0.56) ACHEALDH1A1HPGDKMT2ANPC1
Nitrogen SCHEMBL8776790 0.75 ACHE (0.38) BACE1SYKACHEALDH1A1HPGD
Nitrogen SCHEMBL11313789 0.73 ACHE (0.37) BACE1SYKACHEALDH1A1HPGD
SCHEMBL8082972 0.73 MAPT (0.60) ACHEALDH1A1HPGDKMT2AAR
Nitrogen SCHEMBL11363866 0.72 ALDH1A1 (0.53) SYKACHEALDH1A1HPGDKMT2A
SCHEMBL1856962 0.72 ALDH1A1 (0.48) ALDH1A1HPGDKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4287228-A ARYLDIAZONIUM SALTS AMERICAN CAN COMPANY (US) 1981-09-01 US claimed
US-4482489-A USEFUL IN DIAZOTYPE SYSTEMS AND AS LATENT POLYMERIZATION INITIATORS JAMES RIVER GRAPHICS, INC. (US) 1984-11-13 US disclosed
US-4287228-A ARYLDIAZONIUM SALTS AMERICAN CAN COMPANY (US) 1981-09-01 US disclosed
US-4287228-A ARYLDIAZONIUM SALTS AMERICAN CAN COMPANY (US) 1981-09-01 US disclosed
US-4071671-A RECORDING MATERIALS AMERICAN CAN COMPANY (US) 1978-01-31 US disclosed
US-4056393-A Method of recording information using a copolymer of glycidyl methacrylate and allyl glycidyl ether AMERICAN CAN COMPANY (US) 1977-11-01 US disclosed
US-4054455-A CATALYTIC PHOTOPOLYMERIZATION AMERICAN CAN COMPANY (US) 1977-10-18 US disclosed
US-4054635-A RECORDING AND STORING INFORMATION AMERICAN CAN COMPANY (US) 1977-10-18 US disclosed
US-3951769-A Epoxide photopolymerizable compositions containing cyclic amides as gelation inhibitor and methods of polymerizing AMERICAN CAN COMPANY (US) 1976-04-20 US disclosed