Nitrogen

Nitrogen

SCHEMBL8776790

COc1cc(-c2ccc(C)cc2)c(OC)cc1S.N#N

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 2/20 0.38
PDGFRB P09619 1/20 0.36
PDGFRA P16234 1/20 0.36
GUSB P08236 1/20 0.36
MGAM O43451 2/20 0.36
GAA P10253 2/20 0.36
SI P14410 2/20 0.36
MGAM2 Q2M2H8 2/20 0.36
BACE1 P56817 1/20 0.36
SYK P43405 1/20 0.35
TUBB4A P04350 2/20 0.35
TUBB P07437 2/20 0.35
TUBA3C P0DPH7 2/20 0.35
TUBA1B P68363 2/20 0.35
TUBA4A P68366 2/20 0.35
TUBB4B P68371 2/20 0.35
TUBB3 Q13509 2/20 0.35
TUBB2A Q13885 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL11313789 0.98 ACHE (0.37) ACHEALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL7089611 0.84 ACHE (0.47) ACHEALDH1A1HPGDPDGFRBPDGFRA
Nitrogen SCHEMBL11320287 0.79 ADORA3 (0.42) ALDH1A1HPGDGAASYKKMT2A
Nitrogen SCHEMBL11324353 0.78 ADORA3 (0.41) ALDH1A1HPGDGAASYKKMT2A
SCHEMBL17251283 0.77 ACHE (0.56) ACHEALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL11060656 0.75 BACE1 (0.38) ACHEALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL11236398 0.75 BACE1 (0.38) ACHEALDH1A1HPGDPDGFRBPDGFRA
SCHEMBL7157992 0.75 ADORA3 (0.44) ALDH1A1HPGDGAASYKKMT2A
Nitrogen SCHEMBL11363866 0.74 ALDH1A1 (0.53) ACHEALDH1A1HPGDSYKCYP3A4
SCHEMBL14446041 0.74 ACHE (0.58) ACHEALDH1A1PDGFRBPDGFRABACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0490515-B1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-15 EP disclosed
US-5480762-A Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed
EP-0490515-A1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-06-17 EP disclosed
US-4701399-A Photosensitive composition with 2-halomethyl-5-substituted-1,3,4-oxadiazole FUJI PHOTO FILM CO., LTD. (JP) 1987-10-20 US disclosed
US-4614701-A COLOR FILTERS, FOR TELEVISION AND LIQUID CRYSTAL DISPLAYS SEKISUI FINE CHEMICAL CO., LTD. (JP) 1986-09-30 US disclosed
US-4399210-A O-NAPHTHOQUINONEDIAZIDE AND A DISCOLORING AGENT FUJI PHOTO FILM COMPANY LTD. (JP) 1983-08-16 US disclosed
US-4279982-A PRINTOUTS; OXADIAZOLE PHOTOINITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1981-07-21 US disclosed
US-4232106-A Photosensitive compositions containing 2-halomethyl-5-vinyl-1,3,4-oxadiazoles as free radical progenitors FUJI PHOTO FILM CO., LTD. (JP) 1980-11-04 US disclosed