Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL872948 | 0.96 | ALDH1A1 (0.43) | ALDH1A1RECQLSMN1; SMN2MAPTL3MBTL1 | |
| Biphenyl SCHEMBL22499956 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1 | |
| Biphenyl SCHEMBL5727622 | 0.90 | ALDH1A1 (0.36) | ALDH1A1RECQLSMN1; SMN2MAPTL3MBTL1 | |
| Biphenyl SCHEMBL10601883 | 0.89 | ALDH1A1 (0.45) | ALDH1A1RECQLSMN1; SMN2MAPTL3MBTL1 | |
| Biphenyl SCHEMBL5898513 | 0.86 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1 | |
| Biphenyl SCHEMBL8192900 | 0.86 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1 | |
| Biphenyl SCHEMBL1147617 | 0.86 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1 | |
| Biphenyl SCHEMBL51202 | 0.86 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1 | |
| Ether SCHEMBL21774921 | 0.86 | MMP3 (0.58) | MAPTRAB9AMMP3BCL2L1LMNA | |
| Biphenyl SCHEMBL10621537 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486350-A | REDUCTION OF SULFOCHLORIDE WITH REDUCING AGENT IN PRESENCE OF HYDRIODIC ACID | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-12-04 | — | — | US | disclosed |