SCHEMBL11061300

SCHEMBL11061300

Cc1cc2[nH]c3ccc(Cl)cc3c(=O)n2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 2/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
PARP1 P09874 1/20 0.47
CHEK1 O14757 2/20 0.45
AURKA O14965 1/20 0.45
DAPK3 O43293 1/20 0.45
JAK2 O60674 1/20 0.45
MAP4K4 O95819 1/20 0.45
ABL1 P00519 1/20 0.45
NTRK1 P04629 1/20 0.45
LCK P06239 1/20 0.45
CSF1R P07333 1/20 0.45
RET P07949 1/20 0.45
MET P08581 1/20 0.45
PDGFRB P09619 1/20 0.45
PIM1 P11309 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9217948 0.82 ALDH1A1 (0.62) CA12CA9CYP1A2GAAHPGD
SCHEMBL11155681 0.80 PTGS2 (0.40) CA12CA9CYP1A2HPGDPARP1
SCHEMBL11060925 0.80 PARP1 (0.42) CA12CA9CYP1A2HPGDPARP1
SCHEMBL11626732 0.78 FEN1 (0.49) CYP1A2HPGDPARP1CHEK1NPC1
SCHEMBL11060422 0.78 HTR6 (0.44) CA12CA9LMNACYP1A2GAA
SCHEMBL11622173 0.77 CYP1A2 (0.42) CYP1A2GAAHPGDPARP1CSF1R
SCHEMBL11377184 0.75 CA12 (0.43) CA12CA9LMNACYP1A2GAA
SCHEMBL11051801 0.74 PARP1 (0.51) CA12CA9CYP1A2HPGDPARP1
SCHEMBL11148472 0.73 PKM (0.60) CA12CA9LMNACYP1A2GAA
SCHEMBL11601785 0.73 CYP1A2 (0.49) CYP1A2HPGDPARP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4461827-A Color photographic recording material containing a non-diffusible dye releaser from which a complexible azo dye is released during development AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1984-07-24 US disclosed