Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 11/20 | 0.50 |
| ▸ | DRD2 | P14416 | 9/20 | 0.50 |
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064495 | 0.95 | DRD2 (0.56) | KDRDRD3DRD2DRD4PDGFRB | |
| SCHEMBL7401607 | 0.78 | DRD3 (0.59) | DRD3DRD2MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7409040 | 0.78 | ESR1 (0.53) | DRD2KDM4EMEN1KMT2ALTA4H | |
| SCHEMBL11065756 | 0.77 | KDM1A (0.55) | DRD3DRD2DRD4HTR1A | |
| SCHEMBL11063730 | 0.76 | TACR2 (0.43) | — | |
| SCHEMBL10668573 | 0.73 | DRD3 (0.71) | DRD3DRD2DRD4HTR1ATMEM97 | |
| SCHEMBL11070987 | 0.73 | DRD2 (0.60) | DRD3DRD2DRD4HTR1A | |
| SCHEMBL11062767 | 0.73 | MAOA (0.66) | DRD3DRD2DRD4 | |
| SCHEMBL11071009 | 0.73 | DRD3 (0.66) | DRD3DRD2PDE3BPDE3AMEN1 | |
| SCHEMBL17848660 | 0.72 | DRD2 (0.63) | DRD3DRD2DRD4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |